Smooth Muscle, Endometrial Stromal, and Mixed Müllerian Tumors of the Uterus

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Myxoid mixed low-grade endometrial stromal sarcoma and smooth muscle tumor of the uterus. Case report.

We report the case of a 73-year-old female with myxoid mixed low-grade endometrial stromal sarcoma and smooth muscle tumor of the uterus. Grossly, the tumor sized 130 x 130 x 100 mm involved the uterine corpus almost in its entirety. Histologically, the tumor consisted of two cell types. In some areas, the tumor cells showed typical features of endometrial stromal tumors and resembled stromal c...

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Malignant mixed Müllerian tumors of the uterus: sonographic spectrum.

OBJECTIVE To describe the sonographic findings for malignant mixed Müllerian tumors (MMMTs) of the uterus with particular emphasis on their features on saline contrast sonohysterography (SCSH) and color Doppler sonography, and to determine how they relate to pathological findings. METHODS The SCSH and color Doppler findings in 29 histologically proven cases of uterine MMMT were reviewed retro...

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Smooth Muscle Tumors of the Uterus Pathology

The diagnosis of uterine leiomyosarcoma is usually straightforward since most clinically malignant smooth muscle tumors of the uterus show the microscopic constellation of hypercellularity, severe nuclear atypia, and high mitotic rate generally exceeding 15 mitotic figures per 10 high-power-fields (MF/10 HPF). Frequently, one or more supportive clinicopathologic features such as perior postmeno...

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Transgelin, a Novel Marker of Smooth Muscle Differentiation, Effectively Distinguishes Endometrial Stromal Tumors from Uterine Smooth Muscle Tumors.

Differentiation between endometrial stromal sarcomas (ESSs) and smooth muscle tumors of the uterus can be challenging. Transgelin, a 22 kDa actin-binding protein has recently been shown to be a smooth muscle specific marker. The goal of this study was to determine whether transgelin could accurately distinguish ESSs from smooth muscle tumors. The expression of transgelin, CD10 and smooth muscle...

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Mixed stromal and smooth muscle tumours of the uterus: a report of two cases.

Mixed stromal and smooth muscle uterine tumours, defined as those containing at least 30% of each component as seen by routine light microscopy, are rare. This report describes the morphological features of two such tumours diagnosed in 44-year-old and 50-year-old females complaining from recurrent uterine bleeding that was unresponsive to medical treatment. Morphological and immunohistochemica...

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ژورنال

عنوان ژورنال: Modern Pathology

سال: 2000

ISSN: 0893-3952,1530-0285

DOI: 10.1038/modpathol.3880055